Plasma membrane imaging with a fluorescent benzothiadiazole derivative

• Pedro H. P. R. Carvalho,
• Jose R. Correa,
• Karen L. R. Paiva,
• Daniel F. S. Machado,
• Jackson D. Scholten and
• Brenno A. D. Neto

Beilstein J. Org. Chem. 2019, 15, 2644–2654, doi:10.3762/bjoc.15.257

• application of water-soluble plasma membrane probes [17][18]. We have been developing a new class of selective bioprobes based on the derivatization of the 2,1,3-benzothiadiazole (BTD) core (Figure 1) [19][20][21][22]. After we disclosed the use of these BTD derivatives as a new class of selective

Correlation of surface pressure and hue of planarizable push–pull chromophores at the air/water interface

• Frederik Neuhaus,
• Fabio Zobi,
• Gerald Brezesinski,
• Marta Dal Molin,
• Stefan Matile and
• Andreas Zumbuehl

Beilstein J. Org. Chem. 2017, 13, 1099–1105, doi:10.3762/bjoc.13.109

• ; membrane pressure; membrane probes; monolayers; Introduction Physical triggers are a major regulator of biological processes. The lateral bilayer membrane pressure, e.g., influences the nucleation [1] and shape changes [2] of lipid domains, it gates mechanosensitive pores [3] and globally organizes cell

• cholesterol, the flipper probes do not influence the membrane packing of DPPC and therefore show true potential as disturbance-free mechanosensitive membrane probes. Experimental Grazing incidence angle X-ray diffraction (GIXD) Grazing incidence angle X-ray diffraction measurements were performed at the PETRA